Editor's Note: Dr Robert Siegel MD, has been very gracious to the Council and has supplied much information, most of it in the polysaccharide area. He delivered two papers at our last seminar. He also consults for aloe companies. If you wish to get in touch with him, please contact the IASC office. Thank You Dr Siegel

 Health problems today are becoming chronic, complex, and resistant. Our immune system is burdening by increasing toxins, stress, aging, sedentary life, financial worries ...No penicillin quick cure Immune drug can be found in today's drug store. Half of Texas medical internist report extreme frustration with a practice limited to symptom therapy not cures. Half our population seeks alternative health answers. "Our health care system is broken."   And yet, answers for our health are growing literally right under our feet. Consider aloe Vera plants acknowledged for health benefits across the globe... and through the ages.What are the benefits (documented) to when we take aloe into our body?

Modern laboratory technology finds hundreds of nutrients in Aloe Vera and a remarkably high level of mannan saccharides. What are the benefits to our health when we take mannans into our body? What is special for our health is that functional mannan/mannose molecules (MMM) are found throughout the major signal pathways of our innate immunity.Literally all organs in our body are protected by mannan glycoprotein (GP) which distinguish patterns of Self versus Non Self. GP mechanisms [signal-ligands-receptors] identify nearly all dangerous micro organisms by their membrane signatures - mannan-molecular badges of identity worn by bacteria, virus, toxins, tumors, disease tissue and more.

Functional mannans are traced through our immune Domains of Recognition, of Binding, and of Activation- and through our body's innate strategies of inflammation, pluripotential macrophages and acute phase reactants, and detoxification mechanisms. Our genetic scripts map for total (MMM) absorption's and renal conservation,specific enzymes for transport and chaperone functions and sophisticated biosynthesis [glyco conjugations within cell organelles] building "smart" glycoproteins (GP) signal structures.

And now we are discovering the molecular language of the first wave immune defenses-especially the Lectins carbohydrate super family---with intense research exploring the serum Mannan Binding Protein. And remarkably, we are discovering a core code of the amino acid sequence required by mannose sensitive proteins.

Therefore, the window of opportunity opens as Aloe Immune science now translates into practical, easy to use, safe nutrient products. Research now describes clinical conditions of allergy, asthma, arthritis, auto- immune suggesting an A-Z possibility of health care products.

Reference:

Science papers by Dr Siegel presented to the Annual International Environmental Conference, 1998. Suggested focus papers from research groups including Drs LR Tizard, I. Danhof, R. McDaniel, S. Gordon, A. Ezekowitz